ABSTRACT

Objective  To analyze the clinical and sociodemographic characteristics and survival of individuals with severe acute respiratory syndrome due to COVID-19 according to the COVID-19 vaccination schedule, Brazil, 2021-2022.

Methods  This was a cohort study based on data from the Influenza Epidemiological Surveillance Information System; the Kaplan-Meier and Survival Tree methods were used to analyze survival.

Results  Among the 559,866 hospitalized cases, a higher proportion of vaccinated individuals was found among female (15.0%), elderly people aged ≥ 80 (34.5%), people from the Southeast region (15.7%), those who did not undergo respiratory support (21.2%) and those who did progress to death (15.2%); the survival curve showed that risk of death for unvaccinated individuals was higher in all age groups (p-value < 0.001); elderly people aged ≥ 80, who did not undergo mechanical ventilation and who had a booster dose had lower risk when compared to their peers who had two doses or were unvaccinated (hazard ratio = 0.64; 95%CI 0.62;0.67).

Conclusion  Lowest risk of death was found in vaccinated individuals, especially those who had two doses or a booster dose as well.

MARTINS NETO, C. ; SILVEIRA, V. N. C. ; SILVA, F. N. ; DIAS JUNIOR, J. J. ; BRANCO, M. R. F. C. ; SANTOS, A. M. ; OLIVEIRA, B. L. C. A. . Clinical-epidemiological characteristics and survival of cases of severe acute respiratory syndrome (SARS) due to COVID-19, according to the COVID-19 vaccination schedule in Brazil, 2021-2022: a prospective study. EPIDEMIOLOGIA E SERVIÇOS DE SAÚDE, v. 32, p. e2023128, 2023.

Publicação

EPIDEMIOLOGIA E SERVIÇOS DE SAÚDE, v. 32, p. e2023128, 2023
http://dx.doi.org/10.1590/s2237-96222023000400003.en

 

Palavras-chave

  • COVID-19
  • SARS-CoV-2
  • Survival Analysis
  • COVID-19 Vaccine
  • Cohort Studies

Autores

  • Carlos Martins Neto
  • Victor Nogueira da Cruz Silveira
  • Fábio Nogueira da Silva
  • José de Jesus Dias Júnior
  • Maria dos Remédios Freitas Carvalho Branco
  • Alcione Miranda dos Santos
  • Bruno Luciano Carneiro Alves de Oliveira